Blar i forfatter "Kleive, Dyre"

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    • Aspirin as secondary prevention in colorectal cancer liver metastasis (ASAC trial): study protocol for a multicentre randomized placebo-controlled trial 

      Yaqub, Sheraz; Bjørnbeth, Bjørn Atle; Angelsen, Jon-Helge; Fristrup, Claus W.; Grønbech, Jon Erik; Hemmingsson, Oskar; Isaksson, Bengt; Juel, Ingebjørg Soterud; Larsen, Peter Nørgaard; Lindell, Gert; Mortensen, Frank V.; Mortensen, Kim Erlend; Rizell, Magnus; Sandström, Per; Sandvik, Oddvar Mathias; Sparrelid, Ernesto; Taflin, Helena; Taskén, Kjetil; Brudvik, Kristoffer Watten; Fretland, Åsmund Avdem; Horn, Arild; Kleive, Dyre; Labori, Knut Jørgen; Lassen, Kristoffer; Røsok, Bård Ingvald; Søreide, Jon Arne; Tholfsen, Tore; Villanger, Olaug; Waage, Anne (Journal article; Tidsskriftartikkel, 2021-09-20)
      Background: Colorectal cancer is one the most common cancers in the western world with increasing incidence. Approximately 50% of the patients develop liver metastases. Resection of liver metastases is the treatment of choice although almost half of the resected patients get recurrence in the liver. Methods: The ASAC trial is a Scandinavian, multicentre, double-blinded, randomized, placebo-controlled ...

    • Centralizing a national pancreatoduodenectomy service: striking the right balance 

      Nymo, Linn Såve; Kleive, Dyre; Waardal, Kim; Bringeland, Erling Audun; Søreide, Jon Arne; Labori, Knut Jørgen; Mortensen, Kim Erlend; Søreide, Kjetil; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-07)
      <i>Background</i> - Centralization of pancreatic surgery is currently called for owing to superior outcomes in higher‐volume centres. Conversely, organizational and patient concerns speak for a moderation in centralization. Consensus on the optimal balance has not yet been reached. This observational study presents a volume–outcome analysis of a complete national cohort in a health system with ...

    • Gastro- or Duodenojejunostomy Leaks After Pancreatoduodenectomy: Single Center Experience and Narrative Literature Review 

      Labori, Knut Jørgen; Tholfsen, Tore; Yaqub, Sheraz; Lassen, Kristoffer; Kleive, Dyre; Waage, Anne (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-15)
      <i>Background and Methods</i> - Gastro- or duodenojejunostomy leaks after pancreatoduodenectomy is rare. This study aims to analyze the incidence, management, and outcome of gastro- or duodenojejunostomy leaks after pancreatoduodenectomy based on a single center experience from 2004 to 2020 with a narrative literature review.<br><br> <i>Results</i> - Of a total of 1494 pancreatoduodenectomies, ...

    • Nasogastric Tube on Demand is Rarely Necessary After Pancreatoduodenectomy Within an Enhanced Recovery Pathway 

      Kleive, Dyre; Sahakyan, Mushegh; Labori, Knut Jørgen; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-06-03)
      <i>Background</i> - Evidence-based guidelines for enhanced recovery (ERAS) pathways after pancreatoduodenectomy (PD) are available. Routine use of nasogatric tube (NGT) after PD is not recommended. This study aims to evaluate the need for NGT reinsertion after PD performed within an ERAS setting.<p><p> <i>Methods</i> - It is a prospective observational study of all patients undergoing PD in ...

    • Prognostic Impact of Resection Margin Status in Distal Pancreatectomy for Ductal Adenocarcinoma 

      Sahakyan, Mushegh A.; Verbeke, Caroline S.; Tholfsen, Tore; Ignjatovic, Dejan; Kleive, Dyre; Buanes, Trond; Lassen, Kristoffer; Røsok, Bård I.; Labori, Knut Jørgen; Edwin, Bjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-22)
      Background. Resection margin status is considered one of the few surgeon-controlled parameters affecting prognosis in pancreatic ductal adenocarcinoma (PDAC). While studies mostly focus on resection margins in pancreatoduodenectomy, little is known about their role in distal pancreatectomy (DP). This study aimed to investigate resection margins in DP for PDAC.<p> <p>Methods. Patients who ...

    • The Role of Preoperative Inflammatory Markers in Pancreatectomy: a Norwegian Nationwide Cohort Study 

      Sahakyan, Mushegh; Kleive, Dyre; Dille-Amdam, Rachel G.; Kjeseth, Trond; Waardal, Kim; Edwin, Bjørn von Gohren; Nymo, Linn Såve; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-15)
      Background and purpose Preoperative infammatory markers, such as Glasgow prognostic score, modifed Glasgow prognostic score and C-reactive protein to albumin ratio, were shown to be associated with prognosis in patients undergoing pancreatectomy for cancer. However, little is known about their predictive role in a Western population.<p> <p>Methods The Norwegian National Registry for Gastrointestinal ...

    • Simultaneous Resection of Primary Colorectal Cancer and Synchronous Liver Metastases: Contemporary Practice, Evidence and Knowledge Gaps 

      Kleive, Dyre; Aas, Eline; Bringeland, Erling Audun; Nesbakken, Arild; Nymo, Linn Såve; Schultz, Johannes Kurt; Søreide, Kjetil; Yaqub, Sheraz (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-03-23)
      The timing of surgical resection of synchronous liver metastases from colorectal cancer has been debated for decades. Several strategies have been proposed, but high-level evidence remains scarce. Simultaneous resection of the primary tumour and liver metastases has been described in numerous retrospective audits and meta-analyses. The potential benefits of simultaneous resections are the eradication ...

    • Variation in use of open and laparoscopic distal pancreatectomy and associated outcome metrics in a universal health care system 

      Søreide, Kjetil; Nymo, Linn Såve; Kleive, Dyre; Olsen, Frank; Lassen, Kristoffer (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-01)
      <i>Background</i> - Universal health care (UHC) should ensure equal access to and use of surgery, but few studies have explored variation in UHC systems. The objective was to describe practice of distal pancreatectomy in Norway covered exclusively by an UHC.<p><p> <i>Methods</i> - Data on all patients undergoing distal pancreatectomy from the Norwegian Patient Register over a 5-year period. ...